| GAME | PICK | COMMENT |
| Davis at Ceres, 7:15 | Davis 31-17 | Spartans have the skill players to score with anyone |
| Sonora at Johansen | Sonora 21-14 | Wildcats looking to QB Matt Relei for leadership |
| Stagg vs. Modesto at MJC | Modesto 24-21 | Panthers may be too large for the Delta Kings |
| East Union vs. Enochs at Downey | Enochs 23-20 | Enochs could match last year's win total right here |
| Atwater vs. Bullard (0-1) at Chukchansi Park | Bullard 30-13 | Bullard coming off strong season in Central Section |
| Madera at Merced | Merced 33-17 | Should be the Stefon Mathis show for the opener |
| Sierra at Buhach Colony (1-0) | Sierra 24-23 | Intriguing matchup between CCC and VOL teams |
| Los Banos (1-0) at Tracy | Los Banos 27-23 | Could the Tigers open with two victories in a row? |
| Granite Bay at Pitman (1-0) | Granite Bay 31-20 | Defending Section D2 champs are loaded |
| Central Valley at Le Grand | Central Valley 34-20 | Hawks have the schedule to get off to a fast start |
| Escalon at Dixon | Escalon 31-17 | Cougars have tough home game vs. Patterson next |
| Linden at Ripon | Ripon 20-17 | Traditional opener has always been competitive game |
| Modesto Chr. at Orestimba | MC 33-14 | MC may have too much offense for Warriors |
| Riverbank at Gustine | Riverbank 23-17 | The winner here builds some big momentum |
| Waterford at Hughson | Hughson 34-16 | Huskies should roll in geographical matchup |
| Ripon Chr. at Delhi, 8 | RC 17-16 | Battle of 21 players (RC) vs. 16 (Delhi) |
| Denair at Hilmar | Hilmar 29-12 | Hilmar should be too much for the Coyotes this year |
| Bret Harte at Livingston | Bret Harte 31-24 | Bullfrogs have tough runner in Robert Sailele |
| McClatchy at Patterson | Patterson 30-20 | Tigers' first of three matchups against DI opponent |
| Truckee (1-0) at Mariposa | Truckee 27-17 | Truckee making a long trip to Mariposa County |
| Bear Creek at Argonaut | Argonaut 20-16 | Argonaut hoping home-field advantage is difference |
| N.H. Chr. vs. Turlock Chr. at Waterford | TC 23-13 | Turlock Christian still riding high from last year |
| Sierra Ridge at Bradshaw Chr. | Sierra Ridge 24-17 | Sierra Ridge should roll against beleaguered foe |
| Calaveras at Weston Ranch, 7 | Calaveras 23-17 | Redskins have new coach, same defensive focus |
| Golden Sierra at Amador, 7 | Amador 30-24 | Amador counting on top quarterback Goggans |
| SATURDAY | ||
| Downey at Golden Valley (0-1), 4 | GV 24-17 | Golden Valley playing at own stadium for first time |
| Central Catholic at Cardinal Newman, 7 | CN 33-30 | Top-notch game between strong small-school teams |
| Will DeBoard last season: 231-57 (.802). | ||
All games start at 7:30 p.m. unless noted. | ||